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Antimicrobial agents in urinary tract infections.
Mayo Clinic Proceedings
|March 1, 1983
Summary
Antimicrobial therapies have long treated urinary tract infections. Modern chemotherapy offers single-dose treatments for acute infections and low-dose suppression for recurrent bacterial infections.
Area of Science:
- Infectious Diseases
- Pharmacology
- Urology
Background:
- Antimicrobial therapy has been the cornerstone for treating urinary tract infections (UTIs) since the sulfonamide era.
- Significant advancements in chemotherapy have emerged for managing UTIs.
Purpose of the Study:
- To highlight innovations in antimicrobial chemotherapy for urinary tract infections.
- To describe current therapeutic strategies for acute and recurrent UTIs.
Main Methods:
- Review of historical and contemporary antimicrobial chemotherapy for UTIs.
- Analysis of treatment modalities including single-dose and low-dose suppression.
Main Results:
- Effective antimicrobial treatments for most UTIs are available.
- Innovations include single-dose regimens for acute bacterial cystitis and acute urethral syndrome.
- Low-dose antimicrobial agents provide effective suppression of recurrent bacteriuria.
Conclusions:
- Modern chemotherapy offers improved and convenient treatment options for urinary tract infections.
- Single-dose and low-dose suppression represent significant advancements in UTI management.