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Updated: Oct 20, 2026

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
Acid-base profile of healthy mongrel Indian familaris canis determined by different techniques under two non-volatile
Abstract:
The acid-base status of healthy mongrel Indian dogs was compared under pentobarbital sodium and alpha-chloralose anaesthesia. The findings showed similarity of canine acid-base profile under the two types of anaesthesia. Comparison among various techniques of determination of acid-base profile indicated accuracy of findings. However, a slight metabolic acidosis was persistently observed in the majority of dogs under both types of anaesthesia.
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First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2 and HCO3− values are examined to...