Related Experiment Video
Updated: Sep 6, 2026

Assessing Murine Resistance Artery Function Using Pressure Myography
Published on: June 7, 2013
[Hyperuricemia in essential hypertension. Considerations on some pathogenic aspects]
Abstract:
Hyperuricaemia was encountered in 29% of 55 subjects with essential hypertension, who had not been treated with anti-hypertensive drugs, as against a 10% incidence in a group with normal blood pressure. No relationship between hyperuricaemia and level of hypertension was found. The normal glomerular filtration, the frequent reduction in uric acid clearance and its correlation with uricaemia are held to be indicative of a tubular defect in the excretion of uric acid, as a cause of hyperuricaemia. The reduction in renal plasma flow and its significant correlation with uricaemia and uric acid clearance are considered probable causes of reduced renal excretion. In conclusion it is hypothesised that hypertension triggers renal haemodynamic disturbances and hence hyperuricaemia.
Related Concept Videos
Hypertension and Regulation of Blood Pressure
Antihypertensive Drugs: Action of Diuretics
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies
Urinary Tract Calculi IV: Nutrition Therapy and Prevention

