Anaphylactic reaction to orthoiodohippurate

A case of an anaphylactic reaction following administration of 125I- and 131I-o-iodohippurate in a 32-year-old woman is reported. The patient had a renography performed because of hematuria. She was known to react to an intravenous pyelography previously performed with an anaphylactic shock. The importance of reporting all adverse reactions to radiopharmaceuticals for central registration is stressed.