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Aspergillus infections of the lumbar disc spaces. Report of three cases

J R Mawk, D L Erickson, S N Chou

    Journal of Neurosurgery
    |February 1, 1983
    PubMed

    Insights

    Aspergillus fungal infections of the lumbar spine are rare but serious. Prompt surgical intervention and antifungal treatment offer the best outcomes for these deep-seated bone infections.

    Area of Science:

    • Mycology
    • Infectious Diseases
    • Orthopedic Surgery

    Background:

    • Lumbar vertebral interspace infections are uncommon, particularly those caused by fungal pathogens.
    • Aspergillus species are increasingly recognized as opportunistic pathogens in healthcare settings.

    Observation:

    • Presents three cases of lumbar vertebral interspace infection caused by Aspergillus.
    • Two patients recovered with aggressive surgical debridement and prolonged antifungal therapy.
    • One patient succumbed to complications arising from antibiotic treatment.

    Findings:

    • Aggressive surgical management combined with extended antifungal administration is crucial for treating deep-seated Aspergillus bone infections.
    • The study highlights the challenges in eradicating mycotic infections in osseous tissues.

    Implications:

    • Clinicians should consider fungal etiologies, especially Aspergillus, in refractory or unusual vertebral infections.
    • Effective management requires a multidisciplinary approach involving infectious disease specialists and orthopedic surgeons.
    • Understanding the evolving landscape of nosocomial and spontaneous infections is vital for patient care.

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