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Injectable collagen: a clinical overview.

W Watson, R L Kaye, A Klein

    Cutis
    |May 1, 1983
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    Injectable bovine collagen effectively corrects skin contour defects from scars and aging. Adverse reactions are minimal, with only 1.3% experiencing temporary inflammation in clinical trials.

    Area of Science:

    • Dermatology
    • Cosmetic Surgery
    • Biomaterials

    Background:

    • Injectable bovine collagen is a widely used dermal filler.
    • It addresses skin contour irregularities caused by scarring, rhytides, and folds.
    • Understanding its efficacy and safety is crucial for dermatological applications.

    Purpose of the Study:

    • To evaluate the effectiveness of injectable bovine collagen for correcting skin contour defects.
    • To assess the rate and nature of adverse reactions associated with its use.
    • To outline optimal injection techniques and patient selection criteria.

    Main Methods:

    • Clinical trials involving 5,109 patients treated with injectable bovine collagen.
    • Documentation of adverse events, focusing on local inflammation.

    Related Experiment Videos

  • Presentation of injection techniques and patient selection guidelines.

    • Main Results:

    • Injectable bovine collagen demonstrated high effectiveness in correcting contour defects.
    • A low rate of adverse reactions was observed.
    • 1.3% of patients experienced temporary local inflammation at the injection site.

    Conclusions:

    • Injectable bovine collagen is a safe and effective option for treating skin contour defects.
    • Proper technique and patient selection are key to successful outcomes.
    • Maintenance of correction may require repeat implantations every 6-24 months.