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Updated: Aug 7, 2026

Isolation and Derivation of Mouse Embryonic Germinal Cells
Published on: October 22, 2009
On the segregation of the germ and somatic cell lines in the embryo
Abstract:
In this paper we argue that the mechanisms underlying the segregation of the somatic and germ cell lines are basically similar. The interaction of the genome with specific cytoplasmic factors is responsible for the restriction of their developmental potencies in the somatic cell lines, and for the prevention of such a restriction in the germ cell line. In particular, it is suggested that meiosis is part of the differentiation program of the germ cells.
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