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Immunonephelometric quantitation of apolipoprotein E in human serum
Abstract:
A laser immunonephelometric procedure for the determination of apolipoprotein E in human serum and lipoprotein fractions was developed. Coefficients of variation were 2.3% within-run, 4.7% between-run. The distribution of apolipoprotein E in various lipoprotein fractions revealed a higher proportion of apolipoprotein E in VLDL in hypertriglyceridaemic subjects (especially marked in Type III patients) than in normal subjects. Laser immunonephelometry appears suitable for the routine measurement of apolipoprotein E.