[Pathogenetic interpretation of changes in cerebral somatosensory evoked potentials in multiple sclerosis]

Somatosensory evoked potentials (SSEP) were studied in 13 healthy persons and in 15 patients with disseminated sclerosis (DS). The amplitude decrease of early components of SSEP (frequently till disappearance of these components), latent period prolongation, asymmetry both of the amplitude and latencies were revealed. Late components with latent periods lasting over 80 ms did not change significantly. In DS, demyelinization is supposed to lead mainly to impairment of well myelinized lemnisc fibers of the somatosensory system in disseminated sclerosis.