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Histopathological changes in selenium-exposed fish.

E M Sorensen, J S Bell, C W Harlan

    The American Journal of Forensic Medicine and Pathology
    |June 1, 1983
    PubMed
    Summary
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    Selenium exposure from man-made effluent caused liver and kidney damage in Redear sunfish (Lepomis microlophus) from Martin Lake. Histopathological changes included necrosis and glomerulonephritis, indicating toxic effects on fish health.

    Area of Science:

    • Environmental toxicology
    • Aquatic toxicology
    • Fish pathology

    Background:

    • Martin Lake in east Texas received selenium-laden effluent from man-made sources.
    • Redear sunfish (Lepomis microlophus) were collected from Martin Lake and a reference lake 8 km upstream.
    • Selenium is a metalloid known for its potential toxicity to aquatic organisms.

    Purpose of the Study:

    • To investigate the histopathological effects of chronic selenium exposure on Redear sunfish.
    • To compare fish health between a contaminated lake (Martin Lake) and a reference site.

    Main Methods:

    • Collected Redear sunfish from Martin Lake and a reference lake.
    • Preserved various organs including hepatopancreas, mesonephros, gonads, heart, spleen, stomach, and gill arches.

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  • Performed histopathological examinations using optical and transmission electron microscopy.
  • Main Results:

    • Livers of Martin Lake fish showed central necrosis, reduced rough endoplasmic reticulum, and increased lysosomes.
    • Kidneys exhibited proliferative glomerulonephritis.
    • Exocrine pancreas showed hypertrophy, disorganization, and altered endoplasmic reticulum structure.
    • Stomach, spleen, gills, heart, and gonads displayed no abnormalities.

    Conclusions:

    • Chronic selenium exposure from effluent significantly impacted Redear sunfish liver and kidney tissues.
    • Histopathological alterations indicate toxic effects of selenium on fish at the cellular and tissue levels.
    • Martin Lake fish accumulated approximately 20 ppm selenium in the liver, correlating with observed pathologies.