Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Post-ECT confusional states associated with elevated serum anticholinergic levels.

F M Mondimore, N Damlouji, M F Folstein

    The American Journal of Psychiatry
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Distinguishing bipolar from unipolar depression: the importance of clinical symptoms and illness features.

    Psychological medicine·2015
    Same author

    Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing.

    Molecular psychiatry·2013
    Same author

    Co-morbid anxiety disorders in bipolar disorder and major depression: familial aggregation and clinical characteristics of co-morbid panic disorder, social phobia, specific phobia and obsessive-compulsive disorder.

    Psychological medicine·2011
    Same author

    A new scale for comprehensive assessment of psychopathology in Alzheimer's disease.

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2011
    Same author

    A genome-wide association study of attempted suicide.

    Molecular psychiatry·2011
    Same author

    25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services.

    Neurology·2009

    High anticholinergic drug levels after electroconvulsive therapy (ECT) increase the risk of post-ECT confusional states. Lower drug levels were associated with a reduced risk in patients undergoing ECT.

    Area of Science:

    • Neuroscience
    • Pharmacology
    • Psychiatry

    Background:

    • Electroconvulsive therapy (ECT) is a treatment for severe mental health conditions.
    • Anticholinergic medications are sometimes used in conjunction with ECT.
    • Post-ECT confusion is a known potential side effect.

    Purpose of the Study:

    • To investigate the relationship between anticholinergic drug levels and the incidence of post-ECT confusional states.
    • To determine if higher anticholinergic burden increases the risk of cognitive side effects after ECT.

    Main Methods:

    • Retrospective analysis of 20 patients undergoing ECT.
    • Measurement of serum anticholinergic drug levels post-ECT.
    • Assessment for the presence and severity of post-ECT confusional states.

    Related Experiment Videos

    Main Results:

    • Patients with high anticholinergic drug levels post-ECT exhibited a greater risk of developing confusional states.
    • A correlation was observed between elevated anticholinergic burden and increased risk of post-ECT confusion.

    Conclusions:

    • Anticholinergic drug levels are a significant factor in the development of post-ECT confusional states.
    • Monitoring and potentially adjusting anticholinergic medication may help mitigate cognitive side effects of ECT.