[Apolipoproteins and glycosylated hemoglobin in the young insulin-dependent diabetic]

Apolipoproteins A and B, total cholesterol, triglycerides, HDL, LDL, VLDL cholesterol and glycosylated hemoglobin levels were measured in 81 children and adolescents with juvenile-onset diabetes. There were 41 males and 40 females aged 7 to 22 years. They were separated into 3 groups depending on severity: G1 (well controlled diabetes), G2 (partly controlled diabetes), G3 (poorly controlled diabetes). In boys, triglycerides levels were significantly high in group G1, apolipoprotein B, total cholesterol, triglycerides, VLDL cholesterol levels and Alc glycosylated hemoglobin were raised in group G3. Furthermore, there was a positive correlation between the percentage of Alc glycosylated hemoglobin and LDL cholesterol level. In girls, triglycerides levels were significantly high in group G1, as were apolipoprotein B, triglycerides and VLDL cholesterol levels in group G2 and apolipoprotein B, triglycerides, LDL cholesterol, VLDL cholesterol levels and the percentage of Alc glycosylated hemoglobin in group G3. A positive correlation between the percentage of Alc glycosylated hemoglobin and LDL cholesterol level was also found.