Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sensorineural deafness in early acquired syphilis.

P Saltiel, C A Melmed, D Portnoy

    The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
    |May 1, 1983
    PubMed
    Summary

    Secondary syphilis can cause bilateral sensorineural hearing loss, often as the only symptom. Prompt treatment with penicillin and prednisone can lead to significant hearing recovery, particularly in early-stage cases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Subgroup analysis in RAISE: a randomized, double-blind phase III study of irinotecan, folinic acid, and 5-fluorouracil (FOLFIRI) plus ramucirumab or placebo in patients with metastatic colorectal carcinoma progression.

    Annals of oncology : official journal of the European Society for Medical Oncology·2016
    Same author

    Combining modules for movement.

    Brain research reviews·2007
    Same author

    Modular organization of spinal motor systems.

    The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2002
    Same author

    Complaints of foodborne illness in San Francisco, California, 1998.

    Journal of food protection·2001
    Same author

    New perspectives on spinal motor systems.

    Nature reviews. Neuroscience·2001
    Same author

    Muscle synergies encoded within the spinal cord: evidence from focal intraspinal NMDA iontophoresis in the frog.

    Journal of neurophysiology·2001

    Area of Science:

    • Neurology
    • Infectious Diseases
    • Otolaryngology

    Background:

    • Syphilis, a sexually transmitted infection, can affect multiple organ systems.
    • Neurosyphilis, a complication of syphilis, can manifest in various neurological forms.
    • Hearing loss is a recognized but less common manifestation of syphilis.

    Observation:

    • A 36-year-old male presented with bilateral sensorineural deafness as the primary sign of secondary syphilis.
    • Cerebrospinal fluid analysis revealed pleocytosis, indicating inflammation.
    • The patient experienced good hearing recovery following treatment with penicillin and prednisone.

    Findings:

    • Early acquired syphilitic deafness often results from meningitis affecting the auditory nerve.
    • Corticosteroid therapy appeared crucial for initial hearing improvement.

    Related Experiment Videos

  • Deafness can be the sole presenting symptom of syphilis in both early and late stages.

    • Implications:

    • This case highlights the importance of considering syphilis in the differential diagnosis of sudden or progressive hearing loss.
    • Early diagnosis and treatment of syphilitic hearing loss are critical for favorable outcomes.
    • Understanding the distinct mechanisms of early versus late syphilitic deafness can guide clinical management.