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Ischemic colitis associated with systemic lupus erythematosus.

R M Gore, C S Marn, G T Ujiki

    Diseases of the Colon and Rectum
    |July 1, 1983
    PubMed
    Summary

    Systemic lupus erythematosus (SLE) can cause severe gastrointestinal issues, including colonic ischemia, infarction, and perforation. This case highlights the critical need to consider SLE in patients presenting with such abdominal emergencies.

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    Area of Science:

    • Gastroenterology
    • Rheumatology
    • Internal Medicine

    Background:

    • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
    • Gastrointestinal (GI) complications are recognized but often underdiagnosed in SLE patients.
    • Understanding the spectrum of GI involvement in SLE is crucial for timely diagnosis and management.

    Observation:

    • A 37-year-old female patient with SLE presented with acute abdominal symptoms.
    • Diagnostic workup revealed colonic ischemia, infarction, and perforation.
    • The patient's condition was directly attributed to complications arising from SLE.

    Findings:

    • This case illustrates a rare but severe gastrointestinal manifestation of SLE.
    • The incidence of GI complications in SLE varies widely across studies.

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  • Prompt recognition and intervention are vital for improving outcomes in SLE-related GI emergencies.

    • Implications:

    • Highlights the importance of a high index of suspicion for GI complications in SLE patients.
    • Underscores the need for integrated care between rheumatology and gastroenterology specialists.
    • Emphasizes the potential for life-threatening GI events in the context of systemic autoimmune disease.