[Systemic and renal hemodynamics in hypertension]

The hemodynamic profile of essential hypertension affects renal function. Renal hemodynamics tend to deteriorate as systemic circulation changes from hyper- to hypokinetic type, mainly due to increased renal vascular resistance and reduced minute blood volume. Under hypokinetic circulation, transition to the next stage of essential hypertension takes form: renal ischemia develops during the formative stage of the disease (stage I), glomerular filtration decreases during its stabilization (stage II) in the presence of renal circulatory insufficiency. Renal hemodynamic changes due to reduced cardiac output take root and are manifested during the next stages of essential hypertension irrespective of systemic circulation variant, thus determining a new level of renal functioning.