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Related Experiment Videos

Spindle cell lipoma. An unusual dermatologic presentation.

H J Brody, H D Meltzer, A Someren

    Archives of Dermatology
    |July 1, 1978
    PubMed
    Summary

    Spindle cell lipoma is a benign tumor that can be mistaken for malignant growths. This case highlights its key features, aiding in accurate diagnosis.

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    Area of Science:

    • Dermatopathology
    • Surgical Pathology

    Background:

    • Spindle cell lipoma is a rare, benign soft tissue tumor.
    • It is characterized by a mixture of mature lipocytes and a prominent spindle cell component.
    • Differential diagnosis includes various benign and malignant lipomatous and spindle cell neoplasms.

    Observation:

    • A 30-year-old woman presented with a nontender subcutaneous mass on the left temple.
    • Histological examination revealed a mixed pattern of mature lipocytes and spindle cells.
    • Spindle cells exhibited palisading and fascicular arrangements, separated by fibrous trabeculae.
    • No cellular atypia or increased mitotic activity was observed.
    • A predominance of mast cells was noted within the tumor stroma.

    Findings:

    • The histological findings are consistent with spindle cell lipoma.
    • The presence of mature lipocytes and a significant spindle cell component with specific architectural patterns are characteristic.
    • The absence of atypia and high mitotic activity supports a benign diagnosis.

    Implications:

    • This case emphasizes the importance of recognizing spindle cell lipoma, particularly in atypical presentations.
    • Accurate histological identification is crucial to differentiate it from malignant tumors, preventing misdiagnosis and inappropriate treatment.
    • This report contributes to the dermatologic literature by illustrating this benign entity in a less common demographic and location.

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