Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experimental urinary bladder reconstruction using a synthetic poly(alpha-amino acids) membrane.

K Koiso, T Komai, T Niijima

    Artificial Organs
    |May 1, 1983
    PubMed
    Summary

    This study shows a biodegradable synthetic membrane effectively supports rabbit bladder tissue regeneration. The graft was well-tolerated, with no complications after one year, indicating its clinical potential.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Resolution of exacerbated rheumatoid arthritis-associated interstitial lung disease under baricitinib treatment.

    Scandinavian journal of rheumatology·2023
    Same author

    Systemic lupus erythematosus with hepatic artery aneurysm and large vessel vasculitis.

    Scandinavian journal of rheumatology·2023
    Same author

    Significance of soil moisture on temperature dependence of Hg emission.

    Journal of environmental management·2021
    Same author

    Efficacy and safety of plasma exchange in interstitial lung diseases with anti-melanoma differentiation-associated 5 gene antibody positive clinically amyopathic dermatomyositis.

    Scandinavian journal of rheumatology·2021
    Same author

    Varicella zoster virus myelitis in a patient with rheumatoid arthritis treated by tofacitinib.

    Scandinavian journal of rheumatology·2020
    Same author

    Tofacitinib rapidly ameliorated polyarthropathy in a patient with systemic sclerosis.

    Scandinavian journal of rheumatology·2017

    Area of Science:

    • Biomaterials Science
    • Regenerative Medicine
    • Urology

    Background:

    • Biodegradable synthetic membranes are being explored for tissue reconstruction.
    • The poly(epsilon-benzyloxycarbonyl-L-lysine) membrane offers potential as a scaffold for tissue regeneration.

    Purpose of the Study:

    • To evaluate the biodegradability and efficacy of a poly(epsilon-benzyloxycarbonyl-L-lysine) membrane as a graft for rabbit urinary bladder reconstruction.

    Main Methods:

    • A full-thickness segmental resection of the rabbit urinary bladder was performed.
    • The resected segment was replaced with the synthetic biodegradable membrane.
    • Animals were monitored for 1 year post-implantation.

    Main Results:

    • The synthetic membrane gradually biodegraded, providing a framework for normal bladder tissue regeneration.

    Related Experiment Videos

  • No urinary tract complications, including bladder stones or infections, were observed.
  • Renal function remained undisturbed, and bladder capacity and function were largely preserved.

    • Conclusions:

    • The biodegradable poly(epsilon-benzyloxycarbonyl-L-lysine) membrane demonstrates suitability for urinary bladder reconstruction.
    • The material supports tissue regeneration and is well-tolerated in vivo.
    • Further clinical investigation is warranted for this promising biodegradable graft.