Related Experiment Video

Updated: Aug 19, 2026

Interfacial Molecular-level Structures of Polymers and Biomacromolecules Revealed via Sum Frequency Generation Vibrational Spectroscopy
09:43

Interfacial Molecular-level Structures of Polymers and Biomacromolecules Revealed via Sum Frequency Generation Vibrational Spectroscopy

Published on: August 13, 2019

[Comparative study of normal and myelogenic immunoglobulin G in monomolecular layers at air-water and oil-water

N A Matveeva, L V Chasovnikova, V V Lavrent'ev

    Biofizika
    |May 1, 1983
    PubMed

    Orientation of normal and 12 abnormal immunoglobulins G (IgG) isolated from serum of patients with multiple myeloma in monomolecular layers at 0.15 M NaCl--air and 0.15 M NaCl--octane interfaces has been studied. Majority of abnormal proteins was found to be oriented vertically at phase border of both types unlike normal human IgG which had horizontal orientation. Abnormal IgG differed from the normal one also by lower resistance to surface denaturation at air--water interface. Thus the monomolecular layer method was demonstrated to be capable of distinguishing normal and abnormal IgG.

    More Related Videos

    Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer10:11

    Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

    Published on: April 19, 2021

    Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces08:05

    Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces

    Published on: September 9, 2022

    Related Concept Videos

    Membrane Fluidity01:23

    Membrane Fluidity

    Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.Fatty acids tails of phospholipids can be either saturated or...
    Asymmetric Lipid Bilayer01:35

    Asymmetric Lipid Bilayer

    Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...