Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postnatal synaptic development of the rat.

A J Miller, M McKoon, M Pinneau

    Brain Research
    |June 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Measurement of Direct-Photon Cross Section and Double-Helicity Asymmetry at sqrt[s]=510  GeV in p[over →]+p[over →] Collisions.

    Physical review letters·2023
    Same author

    Letter from A. J. Miller, M. D.

    The Chicago medical journal·2023
    Same author

    Modes and Mechanisms of Pacific Decadal-Scale Variability.

    Annual review of marine science·2022
    Same author

    Growth and Sporulation Potential of Clostridium perfringens in Aerobic and Vacuum-Packaged Cooked Beef.

    Journal of food protection·2019
    Same author

    Combined Water Activity and Solute Effects on Growth and Survival of Listeria monocytogenes Scott A.

    Journal of food protection·2019
    Same author

    Microbiology and Composition of Snack Sausages.

    Journal of food protection·2019

    Synaptic development in the rat nucleus tractus solitarius (NTS) rapidly increases in the first 10 postnatal days. The number of boutons stabilizes, but their contact sites shift from dendrites to cell bodies after day 10.

    Area of Science:

    • Neuroscience
    • Developmental Biology
    • Cell Biology

    Background:

    • The nucleus tractus solitarius (NTS) plays a crucial role in autonomic functions.
    • Understanding early synaptic development in the NTS is vital for comprehending neural circuit formation.

    Purpose of the Study:

    • To investigate the developmental changes in presynaptic boutons in the dorsomedial NTS of rats during the first 30 postnatal days.
    • To quantify the numerical density, volumetric fraction, and synaptic site distribution of boutons.

    Main Methods:

    • Utilized electron microscopy and stereological techniques for quantitative analysis.
    • Examined presynaptic boutons on dendrites and cell bodies in the NTS.

    Main Results:

    Related Experiment Videos

  • Numerical density and volumetric fraction of boutons increased significantly within the first 10 postnatal days.
  • Bouton density remained stable from day 10 to 30.
  • Synaptic contacts shifted from predominantly dendrites to cell bodies after the first 10 days.

    • Conclusions:

    • Presynaptic structure in the NTS undergoes rapid development in early postnatal life.
    • A significant shift in synaptic contact sites occurs during this critical developmental window.