Related Experiment Video
Updated: Feb 10, 2026

Author Spotlight: Standardization and Best Practices for Advancing Lung Imaging Using 129Xe MRI
Published on: November 21, 2023
Abstract:
Irradiation of thyroid glands in rats at a dose rate of approximately 1 rad/day from continually ingested 129I resulted in no significant increase in thyroid tumors compared to controls, nor in other thyroidal effects, nor was there any difference in longevity between the two groups. Marked decreases in 131I uptake by thyroid glands of 129I-fed rats were observed, but these decreases reflected "blocking" of the thyroid by the large quantities of iodine required because of the low specific activity of 129I. In view of the lack of effects on the thyroid gland invoked by lifetime exposures to 129I, and considering the low specific activity of the radionuclide and the limited capacity of the thyroid gland for iodine, the hazard from 129I appears to be extremely limited.
Related Concept Videos
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
Buffer Effectiveness
The buffer capacity is the amount of acid or base that can be added to a given volume...
Drugs Affecting Neurotransmitter Release or Uptake
Framing Effects
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...

