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Updated: Aug 12, 2026

Generation and Quantitative Characterization of Functional and Polarized Biliary Epithelial Cysts
Published on: May 16, 2020
Epidermoid cysts of the liver
Insights
Two new pediatric liver epidermoid cysts were identified, adding to the four known cases. Treatment options include surgical excision or Roux-en-Y cystjejunostomy for palliation due to malignant potential.
Area of Science:
- Hepatology
- Pediatric Surgery
- Surgical Pathology
Background:
- Epidermoid cysts of the liver are rare, with only four cases previously documented.
- The etiology of hepatic epidermoid cysts remains largely unknown, with theories suggesting origins from accessory foregut buds.
Observation:
- Two new cases of liver epidermoid cysts in pediatric patients are presented.
- One case involved a 4-year-old girl with biliary cirrhosis, treated with Roux-en-Y cystjejunostomy.
- The second case was a 5-month-old boy treated with enucleation.
Findings:
- The study expands the known cases of liver epidermoid cysts to six.
- The origin of these cysts is still undetermined.
- The potential for malignancy necessitates aggressive treatment.
Implications:
- Surgical excision is the recommended treatment for liver epidermoid cysts due to their malignant potential.
- Roux-en-Y cystjejunostomy serves as a viable palliative option when complete excision is not feasible.
- These cases highlight the importance of considering epidermoid cysts in pediatric liver pathology.
Abstract:
To the four recorded cases of epidermoid cysts of the liver are added two cases recently seen in children. One was in a 4-yr-old girl and associated with biliary cirrhosis. The other was in a 5-mo-old boy. The former was treated by roux-en-y cystjejunostomy, the latter by enucleation. The origin of these cysts is unknown. One theory suggests derivation from accessory foregut buds. Because of their malignant potential, treatment should be by excision. Where this is impossible, roux-en-y cystjejunostomy offers satisfactory palliation.
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