Ochronosis of prostate presenting as advanced carcinoma

Ochronosis is the clinical manifestation of alkaptonuria, a rare inborn error of metabolism. It is characterized by widespread pigmentation of the fibroconnective tissues, arthritis, and passage of dark urine. Prostatic involvement is usually limited to the incidental finding of calculi within the gland. Herein, we report a case of diffuse ochronotic involvement of the prostate clinically presenting as a neoplasm.