Related Experiment Video

Updated: Aug 14, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Stroke in children. Clinical characteristics and prognosis

O Eeg-Olofsson, Y Ringheim

    Acta Paediatrica Scandinavica
    |May 1, 1983
    PubMed

    Insights

    Childhood stroke, including hemorrhagic and ischemic types, requires prompt medical attention. Early diagnosis and specialized care are crucial for improving outcomes in pediatric stroke patients, despite significant mortality and disability rates.

    Area of Science:

    • Pediatric Neurology
    • Cerebrovascular Diseases
    • Childhood Stroke

    Background:

    • Childhood stroke, characterized by acute hemiplegia, is a significant concern.
    • Prompt intervention is essential to improve patient outcomes.

    Purpose of the Study:

    • To investigate the clinical characteristics, incidence, and outcomes of stroke in children.
    • To offer guidelines for the emergency management of pediatric stroke.

    Main Methods:

    • Retrospective analysis of 27 children diagnosed with stroke over a ten-year period.
    • Inclusion of neuroradiological examinations and neurosurgical interventions where applicable.
    • Analysis of clinical signs, preceding infections, and patient outcomes.

    Main Results:

    • Hemorrhagic stroke occurred in 14 cases, ischemic in 11; 2 cases of migraine accompagnée were also noted.
    • Higher incidence of unilateral neurological signs in ischemic stroke (90%) versus hemorrhagic stroke (50%).
    • Mortality rates were 36% for hemorrhagic and 18% for ischemic stroke, with 75% residual disability in survivors.

    Conclusions:

    • The average annual incidence of childhood stroke is 2.1/100,000.
    • Emphasizes the risks of brain edema and lumbar puncture in pediatric stroke.
    • Urgent transfer to a specialized neurosurgical and neuroradiological facility is critical for affected children.

    More Related Videos

    Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats07:56

    Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

    Published on: April 21, 2017

    Optimized Management of Endovascular Treatment for Acute Ischemic Stroke09:21

    Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

    Published on: January 18, 2018

    Related Concept Videos

    Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

    Aneurysm II: Clinical Manifestations and Diagnostic Studies

    Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
    Stroke: Introduction and Types01:29

    Stroke: Introduction and Types

    A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
    Ischemic Stroke l: Introduction01:15

    Ischemic Stroke l: Introduction

    Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
    Ischemic Stroke ll: Pathophysiology01:15

    Ischemic Stroke ll: Pathophysiology

    An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
    Hemorrhagic Stroke l: Introduction01:17

    Hemorrhagic Stroke l: Introduction

    A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
    Hemorrhagic Stroke ll: Pathophysiology01:29

    Hemorrhagic Stroke ll: Pathophysiology

    A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...