[Selective autotransplant of the spleen. An experimental study]

A study was carried out on 40 dogs. Four groups of ten dogs each were established. A laparotomy group, a simple splenectomy group and two groups which underwent a selective autotransplant of the medium an deep layers of a centrifugated solution of splenic medulla respectively. Immunisation with BSA showed that humoral immune response with formation of anti-BSA antibodies is more intense in the control group which underwent laparotomy than in the splenectomised group. The response obtained in dogs subjected to autotransplant of deep layer is almost identical to that of the control group while that of the medium layer showed a slightly lower response. Cellular immune response is more accentuated in the group which underwent autotransplant from the deep layer, while those from the medium layer showed a higher response than that of the splenectomised group.