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[Radioimmunoassay for screening studies in the newborn]
Insights
Newborn screening identified 111 infants with transient hyperthyroidism. Maternal endocrine issues and complicated pregnancies were key causes, impacting infant adaptation and thyroid function.
Area of Science:
- Neonatal endocrinology
- Thyroid function testing
- Public health screening
Abstract:
A radioimmunological examination (screening) of hypophyseal-thyroid function in 2400 newborns within the 1st week of life revealed 111 infants with transitory forms of hyperthyroidism that was observed during the 1st month of the life. The main causes of disturbed thyroid function were endocrine diseases in mothers, a complicated course of pregnancy and delivery. It made it possible to detect not only congenital thyroid diseases but also to evaluate the function of the most important hormonal system in the adaptation of an infant in the postnatal period.