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Related Experiment Videos

Trace elements in human milk.

F J Cumming, J J Fardy, M H Briggs

    Obstetrics and Gynecology
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    This study analyzed elemental concentrations in Australian women's blood plasma and milk. Lactation stage significantly impacts element transfer, with implications for infant nutrition, but contraceptives showed no effect.

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    Area of Science:

    • Human Physiology
    • Nutritional Science
    • Trace Element Analysis

    Background:

    • Understanding elemental composition in maternal blood and milk is crucial for infant nutrition.
    • Lactation involves complex physiological changes affecting nutrient transfer.
    • Baseline data on trace elements in lactating women is essential for nutritional assessment.

    Purpose of the Study:

    • To determine baseline elemental concentrations in blood plasma and milk of lactating Australian women.
    • To investigate factors influencing elemental partitioning between plasma and milk during lactation.
    • To assess the nutritional implications of these changes for exclusively breast-fed infants.

    Main Methods:

    • Multielement neutron activation analysis (NAA) was employed for precise elemental quantification.

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  • Blood plasma and milk samples were collected from a cohort of lactating Australian women.
  • Factors affecting element concentrations and plasma-to-milk transfer were analyzed.

    • Main Results:

    • Baseline values for nine essential elements were established in blood plasma and milk.
    • Significant changes in the partitioning of elements between plasma and milk were observed as lactation progressed.
    • Progestogen-only oral contraceptives did not significantly alter trace element levels in blood or milk.

    Conclusions:

    • The progression of lactation dynamically alters the transfer of elements from plasma to milk.
    • These alterations have direct nutritional consequences for exclusively breast-fed infants.
    • Hormonal contraception (progestogen-only) does not appear to interfere with essential trace element homeostasis during lactation.