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Updated: Aug 18, 2026

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
Published on: June 28, 2019
[Effect of molsidomine on cardiac function in experimental transitory coronary insufficiency]
Abstract:
Increased resistance of the heart to acute transitory coronary insufficiency under conditions of prophylactic use of molsidomin was demonstrated in experiments on dogs and rats. The agent prevents electric destabilization of the heart. Reduction of pre- and postexertion of the heart is one of the main factors of the protective action of molsidomin. It is suggested that the drug may be included in the complex of measures used in the treatment of patients suffering from anginal and anginal-arrhythmic forms of stable and unstable angina pectoris.
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