[Effect of the thymic factor on blood coagulation and fibrinolysis in thymectomized rats]

Hypercoagulation and fibrinolysis inhibition are seen in adult rats 6 to 6 1/2 months after thymectomy. Hemocuagulation accelerating is caused by the shortened 1st phase of the blood coagulation process. Fibrinolysis delay is partially produced by a decrease in the fibrinalytic agent concentration and smooth elevation of the antiplasmin level. The most part of the coagulogram indices and fibrinolysis activation returns to normal in operated animals following the injection of a low-molecular polypeptide thymic factor within 5 days.