Urographic excretion studies: preliminary results with a six-iodine, singly-ionizing sodium salt--P.286

Preliminary results of comparative studies with a new water-soluble contrast agent are described. The new agent, with the code P.286, is a molecule with 6 iodine atoms attached and only one ionizing group. The sodium salt of the new agent has been compared with sodium iothalamate and metrizamide in dogs. The results suggest that the sodium salt of P.286 is superior in terms of urinary iodine concentration to both sodium iothalamate and metrizamide.