Fluoride concentrations in fissure and cervical enamel of unerupted human teeth

Fluoride concentration of fissure enamel from unerupted third molars was higher than that of the cervical-lingual but not cervical-buccal surfaces at a similar depth of the removed enamel. The highest fluoride concentration was found in the fissure enamel due probably to its earlier formation, higher permeability and embedding tissue before eruption.