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Computed tomographic brain scanning in patients with lymphoma
Radiology
|October 1, 1978
Summary
Computed tomographic (CT) brain scans effectively detect lymphoma in the brain and orbit. However, CT scans struggle to identify dural and leptomeningeal lymphoma, though serial scans aid in differentiating non-lymphomatous lesions.
Area of Science:
- Neurology
- Radiology
- Oncology
Background:
- Lymphoma can affect the central nervous system, including the brain and orbit.
- Accurate detection of these involvements is crucial for patient management.
- Computed tomography (CT) is a common imaging modality used in oncology.
Purpose of the Study:
- To evaluate the sensitivity of computed tomographic (CT) brain scans in detecting lymphoma.
- To assess the utility of CT scans in differentiating lymphomatous from non-lymphomatous brain lesions.
Main Methods:
- A retrospective analysis of 118 lymphoma patients.
- Review of computed tomographic (CT) brain scans.
Main Results:
- CT scans demonstrated high sensitivity for detecting lymphoma in the brain parenchyma and orbit.
- Brain parenchymal lymphoma was specifically observed in diffuse histiocytic lymphoma cases.
- Dural infiltration was less consistently detected.
- Leptomeningeal lymphoma was not directly visualized, even with contrast enhancement.
- Serial CT scans proved valuable in distinguishing non-lymphomatous brain lesions.
Conclusions:
- CT brain scans are valuable for identifying orbital and brain parenchymal lymphoma.
- CT imaging has limitations in detecting leptomeningeal and some dural lymphoma.
- Serial CT scans assist in the differential diagnosis of brain lesions in lymphoma patients.