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Dissolution rate behavior of fluoridated apatite pellets

M Okazaki, Y Moriwaki, T Aoba

    Journal of Dental Research
    |November 1, 1981
    PubMed
    Summary
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    Synthetic fluoridated apatite dissolution rates decrease with increasing fluoride content, especially at low levels. This finding impacts understanding of fluoride

    Area of Science:

    • Materials Science
    • Biomaterials Science
    • Chemical Engineering

    Background:

    • Fluoridated apatite is crucial in dental materials and bone regeneration.
    • Understanding its dissolution behavior is key to predicting material performance and stability.
    • Fluoride incorporation significantly alters apatite properties.

    Purpose of the Study:

    • To quantify the effect of fluoride content on the dissolution rate of synthetic fluoridated apatite.
    • To investigate the relationship between fluoride incorporation and apatite dissolution kinetics.
    • To analyze dissolution data using a diffusion-controlled model.

    Main Methods:

    • Preparation of synthetic fluoridated apatite pellets with varying fluoride content.
    • Measurement of dissolution rates in an acetate buffer solution at pH 4.0.

    Related Experiment Videos

  • Analysis of experimental data using a diffusion-controlled model.
  • Comparison of dissolution rates with solubility data.

    • Main Results:

    • Dissolution rate of fluoridated apatite decreases as fluoride content increases.
    • A significant decrease in dissolution rate is observed at lower fluoride concentrations.
    • The diffusion-controlled model indicates that initial dissolution rate is influenced by solubility and mass transfer resistance.
    • Fluoride content directly affects the overall mass transfer resistance.

    Conclusions:

    • Fluoridation effectively reduces the dissolution rate of synthetic apatite.
    • The study provides insights into the mechanism of fluoridated apatite dissolution.
    • Mass transfer resistance, influenced by fluoride content, plays a critical role in controlling dissolution kinetics.