Acute myeloblastic leukemia following chemotherapy for mycosis fungoides

The development of acute myeloblastic leukemia following therapy for malignant disorders is being recognized with increasing frequency. Acute myeloblastic leukemia (erythroleukemic variant) developed in a patient with mycosis fungoides following three years of chemotherapy with a variety of antineoplastic drugs. The patient demonstrated a hypodiploid chromosomal abnormality with a missing C group chromosome.