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Updated: Aug 4, 2026
12:27
Quantifying the Cytotoxicity of Staphylococcus aureus Against Human Polymorphonuclear Leukocytes
Published on: January 3, 2020
Staphylococcal toxic shock: two fulminant cases with recovery
The New Zealand Medical Journal
|March 10, 1982
Summary
Toxic shock syndrome (TSS) in young women using tampons is rare but serious. Early intensive care is crucial for recovery, even with severe complications like organ failure.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
Background:
- Toxic shock syndrome (TSS) is a rare, life-threatening condition.
- Staphylococcus aureus is a common bacterium that can cause TSS.
Observation:
- Two young women presented with severe TSS symptoms, including diarrhea, confusion, collapse, and rash.
- Both patients were menstruating and using tampons at illness onset.
- One patient developed disseminated intravascular coagulation, rhabdomyolysis, myoglobinuria, and renal failure.
Findings:
- Staphylococcus aureus was cultured from vaginal and fecal samples.
- Vigorous intensive care, including peritoneal dialysis for renal failure, was essential for recovery.
- Prompt and aggressive medical intervention is key to managing severe TSS cases.
Implications:
- Highlights the importance of recognizing and rapidly managing TSS, particularly in menstruating women using tampons.
- Emphasizes the critical role of intensive care in improving outcomes for severe TSS.
- Suggests continued vigilance for Staphylococcus aureus-related infections in susceptible populations.
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