Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plague in Central Java, Indonesia

J E Williams, B W Hudson, R W Turner

    Bulletin of the World Health Organization
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    MR Imaging Characteristics of Intraocular Perfluoro-n-Octane.

    AJNR. American journal of neuroradiology·2020
    Same author

    Microbiota of bovine milk, teat skin, and teat canal: Similarity and variation due to sampling technique and milk fraction.

    Journal of dairy science·2020
    Same author

    Bioelectric impedance vector analysis (BIVA) in hospitalised children; predictors and associations with clinical outcomes.

    European journal of clinical nutrition·2019
    Same author

    Body mass index adjustments to increase the validity of body fatness assessment in UK Black African and South Asian children.

    International journal of obesity (2005)·2017
    Same author

    The use of high-intensity focused ultrasound as a novel treatment for painful conditions-a description and narrative review of the literature.

    British journal of anaesthesia·2015
    Same author

    Routine screening for pain combined with a pain treatment protocol in head and neck cancer: a randomised controlled trial.

    British journal of anaesthesia·2015
    Same journal

    Diplomatic roles of regional coordinators for WHO Member States.

    Bulletin of the World Health Organization·2026
    Same journal

    Evaluation of an application for investments in cataract surgery, Ethiopia.

    Bulletin of the World Health Organization·2026
    Same journal

    An umbrella protocol for the clinical evaluation of diagnostics in infectious disease.

    Bulletin of the World Health Organization·2026
    Same journal

    Fundamental changes in regulation to improve access to biosimilars.

    Bulletin of the World Health Organization·2026
    Same journal

    A public-private partnership for facility-based tuberculosis screening using chest radiographs, Viet Nam.

    Bulletin of the World Health Organization·2026
    Same journal

    Ebola at a critical juncture: preparedness must outpace transmission.

    Bulletin of the World Health Organization·2026
    See all related articles

    Plague outbreaks in Java between 1968-1974 were linked to infected fleas and rats in mountain villages. Continued surveillance is vital due to the persistence of Yersinia pestis, the plague bacterium.

    Area of Science:

    • Zoonotic diseases
    • Epidemiology
    • Microbiology

    Background:

    • Human plague cases were documented in Boyolali Regency, Central Java, from 1968 to 1970.
    • Rodent plague investigations confirmed the persistence of Yersinia pestis in the region between 1972 and 1974.

    Purpose of the Study:

    • To investigate the persistence and transmission dynamics of plague in Central Java.
    • To identify the sources and risk factors associated with human plague infections.

    Main Methods:

    • Field investigations involving the collection of infected fleas and rodents.
    • Isolation and identification of Yersinia pestis from environmental samples.
    • Serological testing of rodent populations to assess plague prevalence.

    Related Experiment Videos

    Main Results:

    • Yersinia pestis was isolated from fleas (Xenopsylla cheopis, Stivalius cognatus) and rats (Rattus rattus diardii, R. exulans ephippium).
    • Human and rodent plague incidence peaked from December to May at elevations above 1000 m.
    • Fleas infected with Y. pestis, particularly those with a unique electrophoretic phenotype, posed the major risk to humans, with infected fleas frequently found in houses.

    Conclusions:

    • Rodent plague, introduced in 1920, had persisted in the Boyolali Regency for at least 54 years.
    • The findings underscore the need for ongoing plague surveillance in the region.
    • Environmental and host factors, including specific flea vectors and elevations, are critical for plague transmission.