Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Central achromatopsia: behavioral, anatomic, and physiologic aspects

A Damasio, T Yamada, H Damasio

    Neurology
    |October 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Molecular biomarkers for assessing the heat-adapted phenotype: a narrative scoping review.

    The journal of physiological sciences : JPS·2025
    Same author

    Ketone monoester ingestion improves cardiac function in adults with type 2 diabetes: a double-blind, placebo-controlled, randomized, crossover trial.

    Journal of applied physiology (Bethesda, Md. : 1985)·2025
    Same author

    Simultaneous Measurement of the Half-Life and Spectral Shape of ^{115}In β Decay with an Indium Iodide Cryogenic Calorimeter.

    Physical review letters·2024
    Same author

    Perioperative neuromuscular blockade monitoring - a comparison between tertiary centres and with existing guidelines.

    Irish medical journal·2024
    Same author

    Molecular biomarkers for assessing the heat-adapted phenotype: a narrative scoping review.

    The journal of physiological sciences : JPS·2023
    Same author

    First Measurement of the Nuclear-Recoil Ionization Yield in Silicon at 100 eV.

    Physical review letters·2023
    Same journal

    Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

    Neurology·2026
    Same journal

    Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

    Neurology·2026
    Same journal

    Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

    Neurology·2026
    Same journal

    Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

    Neurology·2026
    Same journal

    Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

    Neurology·2026
    Same journal

    At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

    Neurology·2026
    See all related articles

    Achromatopsia, a color perception deficit, was studied in two patients. Lesions in the occipital lobe correlated with achromatopsia, with prosopagnosia appearing in the bilateral case.

    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Cognitive Psychology

    Background:

    • Achromatopsia is a rare genetic or acquired condition characterized by a complete or partial loss of color vision.
    • Understanding the neural basis of achromatopsia is crucial for diagnosing and managing visual processing disorders.

    Purpose of the Study:

    • To investigate the neuropsychologic, neuroanatomic, and neurophysiologic correlates of achromatopsia.
    • To examine the relationship between lesion location and associated cognitive deficits, such as prosopagnosia.

    Main Methods:

    • Case study of two patients with achromatopsia.
    • Neuropsychologic assessments to evaluate cognitive functions.
    • Neuroanatomic imaging to identify lesion locations.
    • Neurophysiologic testing using cerebral evoked responses to pattern shift stimulation.

    Related Experiment Videos

    Main Results:

    • Both patients had lesions in the ventromedial occipital lobe.
    • Prosopagnosia (face recognition deficit) was present in the patient with bilateral lesions but not in the patient with unilateral lesions.
    • Cerebral evoked responses were abnormal for red-green stimulation in the achromatopsic visual field, but normal for black and white stimulation.

    Conclusions:

    • The ventromedial occipital lobe is implicated in achromatopsia.
    • The presence of prosopagnosia may be associated with the extent (bilateral vs. unilateral) of occipital lobe damage.
    • Neurophysiologic testing can reveal functional deficits in color processing corresponding to achromatopsia.