Local potassium concentration changes in the retina and the electroretinographic (ERG) b-wave

Intraretinal injections of high- and low-K+ Ringer's solutions generate potentials which are opposite in polarity but otherwise similar in both their shapes and retinal depth profiles. We provide evidence that the principal generator of the K+-mediated potential is the Müller (glial) cell, but that the FRG b-wave cannot be explained solely by this K+-mediated potential without considering involvement of the electrical activities of neuronal cells.