[Morpho-functional changes in the frog neurons in ischemia]

After the full spinal cord ishemia in the frog, motoneuron lose their ability to generate spike potentials to a testing stimulation in 30 minutes. The size and structure of these neurons do not differ from those in the control ones. The ten minute high frequency stimulation of motoneurons affected by ishemia results in deep pathologic structural changes. The neuron dimensions decrease, and numerous picnomorphical, dark and vaculized neurons appear. The full ishemia leads to pathologic changes in the neuron structure. However, the number of picnomorphical and dark neurons is considerably less than that after the high frequency activation. Following the 90 minute ishemia, no postsynaptic or spike potentials occur in motoneurons as a response to their stimulation.