[Behavior of mast cells in experimental burns in rats]

The Authors, using a personal dyeing method, specific for mast cells, that they described in a former work, (a modification of May-Gruenwald-Giemsa dye) observed crowd of mast cells in the subcutaneous tissue, below the site of thermal skin burns, in rats. They clearly demonstrate the phenomenon of mast cells degranulation. The granules are released in the subcutaneous tissue, then they go away along the limph vessels, and it is possible to follow them until the limph nodes. There is also crowd of limphocytes and plasma cells; nevertheless, there is evidence that mast cells are the early cells which react to burns in rats. Perhaps it should be possible that mast cells have some immunological function, owing to the contact their granules take with lymphocytes and plasma cells.