Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Large cell lymphocytoma

S C Duncan, H L Evans, R K Winkelmann

    Archives of Dermatology
    |October 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    This study identified a distinct histologic pattern in nine cutaneous lymphoproliferative disease cases. These benign lesions, initially misdiagnosed as lymphoma, showed unique lymphocyte patterns upon further evaluation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mn-salen catalysed benzylic C-H activation for the synthesis of aryl [(18)F]CF3-containing PET probes.

    Chemical communications (Cambridge, England)·2015
    Same author

    Reconstruction of the symphysis pubis to repair a complex midline hernia in the setting of congenital bladder exstrophy.

    Hernia : the journal of hernias and abdominal wall surgery·2014
    Same author

    Effect of corn dried distillers grains with solubles, conjugated linoleic acid, and ractopamine (paylean) on growth performance and fat characteristics of late finishing pigs.

    Journal of animal science·2012
    Same author

    The effect of corn distiller's dried grains with solubles, ractopamine, and conjugated linoleic acid on the carcass performance, meat quality, and shelf-life characteristics of fresh pork following three different storage methods.

    Meat science·2011
    Same author

    A Case of Traumatic Tetanus which Recovered under Antitoxin Injections.

    British medical journal·2010
    Same author

    Outbreak of carbapenem-resistant Acinetobacter baumannii among non-burn patients in a burn intensive care unit.

    The Journal of hospital infection·2010
    Same journal

    Scoring With SCORTEN-Reply.

    Archives of dermatology·2017
    Same journal

    Comparison of Early and Late Latent Syphilis- Colorado, 1991.

    Archives of dermatology·2016
    Same journal

    Case of Rhinoscleroma.

    Archives of dermatology·2016
    Same journal

    Cutaneous Fungal Infections.

    Archives of dermatology·2016
    Same journal

    An Ulcerated Plaque in a Gay Man.

    Archives of dermatology·2016
    Same journal

    Solitary Violaceous Nodule on the Face.

    Archives of dermatology·2016
    See all related articles

    Area of Science:

    • Dermatology
    • Hematopathology
    • Oncology

    Background:

    • Cutaneous lymphoproliferative diseases present diagnostic challenges.
    • Accurate diagnosis is crucial for appropriate patient management and prognosis.
    • Distinguishing benign from malignant conditions is paramount.

    Observation:

    • Nine cases of cutaneous lymphoproliferative disease with a specific histologic pattern were analyzed.
    • Lesions presented as red-to-violaceous, deep papules or nodules, single or clustered.
    • Histologic examination revealed nodular infiltrates of large, pleomorphic lymphocytes with frequent mitoses.

    Findings:

    • A distinct pattern characterized by dense clusters of small lymphocytes surrounding or infiltrating large cells was observed.
    • This pattern, termed large cell lymphocytoma, was not associated with progressive malignant lymphoma.

    Related Experiment Videos

  • Seven cases were initially misdiagnosed as lymphoma or reticulum cell sarcoma.
  • All patients demonstrated benign disease on long-term follow-up, with no evidence of malignant lymphoma.

    • Implications:

    • The findings suggest a specific benign entity that can mimic malignant lymphoma histologically.
    • Recognition of this distinct pattern is essential to avoid misdiagnosis and unnecessary aggressive treatment.
    • Multiple biopsies may be required to establish the correct diagnosis.
    • Long-term follow-up confirmed the benign nature of these cutaneous lymphoproliferative lesions.