[Studies on the use of tissue adhesives in cataract microsurgery]

Corneal incision employed according to Paufique's method for microsurgical cataract removal was dressed with cyanoacrylic adhesive Histoacryl n-blau after the previous wound filling with biological adhesive from freeze dried human plasma. The experiments were performed on 80 enucleated cattle eyeballs and on 60 eyeballs of rabbits. The material were divided into groups depending on the method of wound dressing. In the I group wounds were dressed with adaptation sutures according to the Liegard method and filled with biological adhesive; cyanoacrylic adhesive was applied supplementary. In the II group wounds were filled with biological adhesive and sutured. In the III group wounds were only sutured. The rabbits were observed for 21 days and the resistance of wound anastomosis examined. In the I group wound resistance immediately after the operation and after 24 hours was found to be two times higher than in other groups. 7 days after the operation the values obtained in all groups were similar. In all groups the eyeballs irritation was similar within the first five days. 7 days after the operation plates of cyanoacrylic adhesive were removed without difficulties. In all groups linear corneal scars with mistiness 2 mm wide was found, also singular blood vessels penetrating the cornea were observed.