Effects of low-level radiation and comparative risk
Related Experiment Video
Updated: Aug 15, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
Published on: July 3, 2015
Abstract:
At low doses of radiation to the whole body, the dose-effect relationship for human must usually be determined by extrapolation from human data at high doses. Reasons for above-linear, linear, or below-linear extrapolation from high doses to low doses are discussed. The linear extrapolation is most common, and probably leads to conservative estimates of risk. Risks from other carcinogens may be compared directly with radiation risk by using cancer incidence as the end point. However, lifeshortening is a more useful index of comparison in many other circumstances, and can be used to compare the time lost due to radiation-induced cancer with that due to accidental deaths and other lost industrial time. Risks for radiation workers exposed at current average occupational dose levels are shown to be comparable with those from other safe industries. Questions of acceptability and public perception of risk are briefly discussed.
More Related Videos
06:20Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
08:23An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
Published on: December 25, 2021
Related Concept Videos
Biological Effects of Radiation
Isotopes and Radioisotopes
An isotope containing more...
Mutagenicity and Carcinogenicity
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Toxicity Testing in Animals
Hazard Ratio
For example, in a clinical trial evaluating a...