Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deep brain stimulation for severe, chronic pain

C D Ray, C V Burton

    Acta Neurochirurgica. Supplementum
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pre-eclampsia and hyponatraemia.

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2006
    Same author

    Symposium: a critical discrepancy-a criteria of successful arthrodesis following interbody spinal fusions.

    Spine·2001
    Same author

    Interbody cages.

    Journal of neurosurgery·2000
    Same author

    Correction for biases in a population-based study of family history and coronary heart disease. The Newcastle Family History Study I.

    American journal of epidemiology·1998
    Same author

    Threaded titanium cages for lumbar interbody fusions.

    Spine·1997
    Same author

    Threaded fusion cages for lumbar interbody fusions. An economic comparison with 360 degrees fusions.

    Spine·1997
    Same journal

    [Psychiatry of brain tumors and the cerebral bases of psychical processes].

    Acta neurochirurgica. Supplementum·2014
    Same journal

    [Arteriography in the differential diagnosis of brain tumors].

    Acta neurochirurgica. Supplementum·2014
    Same journal

    The endogenous ouabain-like sodium pump inhibitor in cold injury-induced brain edema.

    Acta neurochirurgica. Supplementum·1994
    Same journal

    Proposed toxic oxidant inhibitors fail to reduce brain edema.

    Acta neurochirurgica. Supplementum·1994
    Same journal

    A novel aspect of thrombin in the tissue reaction following central nervous system injury.

    Acta neurochirurgica. Supplementum·1994
    Same journal

    Causative role of lysosomal enzymes in the pathogenesis of cerebral lesions due to brain edema under chronic hypertension.

    Acta neurochirurgica. Supplementum·1994
    See all related articles

    Deep brain stimulation in the parafascicularis-centre-median area (pf-CM) effectively treats chronic pain. This method provided significant pain relief in 76% of patients, demonstrating its therapeutic potential.

    Area of Science:

    • Neurosurgery
    • Pain Management
    • Neuromodulation

    Background:

    • Severe chronic pain often requires advanced treatment options.
    • The parafascicularis-centre-median area (pf-CM) of the thalamus is implicated in pain processing.

    Purpose of the Study:

    • To evaluate the efficacy of deep brain stimulation (DBS) in the pf-CM for chronic pain relief.
    • To assess the long-term outcomes and predictive value of intraoperative testing for pf-CM DBS.

    Main Methods:

    • Twenty-eight patients with severe chronic pain received deep brain electrodes in the pf-CM.
    • Electrical stimulation was applied for varying durations.
    • Intraoperative test stimulation was used to predict outcomes.
    • New surgical devices for electrode placement and anchoring were also presented.

    Related Experiment Videos

    Main Results:

    • Good-to-excellent pain relief (≥50% reduction) was achieved in 76% of patients.
    • Intraoperative test stimulation accurately predicted successful long-term outcomes.
    • Electrodes were implanted for periods ranging from days to months.

    Conclusions:

    • Deep brain stimulation of the pf-CM is a viable and effective treatment for selected patients with severe chronic pain.
    • Intraoperative testing is a valuable tool for patient selection and outcome prediction.
    • Novel surgical adjuncts may improve the delivery and management of DBS therapy.