Related Experiment Video
Updated: Aug 13, 2026

Coculture Analysis of Extracellular Protein Interactions Affecting Insulin Secretion by Pancreatic Beta Cells
Published on: June 15, 2013
Insulin binding to its receptor: is the receptor more important than the hormone?
Abstract:
The development of methods to measure insulin showed that many (if not most) patients with disorders of glucose metabolism have a target cell disorder rather than a secretory defect. Methods to measure the insulin receptor have shown that in patients with target cell disorders the receptor is often involved in a meaningful way. Furthermore, even in diseases where hormone secretion (deficiency or excess) is dominant, the receptor may play an important role in the clinical state of the patients. In the future, development of techniques to assess postreceptor events should uncover defects at these sites as well.
More Related Videos
08:32Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain
Published on: January 4, 2018
08:34Precise Visualization of Insulin Receptors A and B in Murine Brain with an RNA In Situ Hybridization Assay
Published on: July 15, 2025
Related Concept Videos
Intracellular Hormone Receptors
Insulin Secretory Vesicles
Spare Receptors
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are co-secreted in...
Insulin: The Receptor and Signaling Pathways