[Morphological types of the changes in the myofibrils of cardiac muscle cells]

Light microscopy and electron microscopy examinations showed the changes in myofibrils to be a criterion of early stages of cardiomyocyte involvement. Proceeding from this, the main types of acute cardiomyocyte damage are distinguished: contractures (segmentary and subsegmentary), primary clump degeneration, intracellular myocytolysis and cytolysis. The best way to detect the state of myofibrils by light microscopy is to use polarization microscopy which diagnoses in sections acute metabolic damages and early stages of myocardial infarction, repeated and relapsing infarctions, fibrillation of ventricles. The utilization of polarization microscopy in pathological practice permits one to diagnose definitely the early stages of acute damages of the heart in cases of sudden and unexpected death.