[Effect of metoclopramide (Cerucal) on postprandial gastroesophageal reflux]

Postcibal provoked gastrooesophageal reflux of 14 patients with symptoms of reflux was reduced significantly by metoclopramide (Cerucal, 10 mg i. v. or p. o.) for a period of at least 4 hours. Especially metoclopramide was effective in patients with severe symptoms and on 2 patients with endoscopically evident oesophagitis. Metoclopramide was ineffective in 4 patients with slight symptoms whereby therapeutic ineffectiveness may result.