Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Precision and accuracy: concepts and assessment by method evaluation testing

J O Westgard

    Critical Reviews in Clinical Laboratory Sciences
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Models for combining random and systematic errors. assumptions and consequences for different models.

    Clinical chemistry and laboratory medicine·2001
    Same author

    Electronic quality control, the total testing process, and the total quality control system.

    Clinica chimica acta; international journal of clinical chemistry·2001
    Same author

    The need for a system of quality standards for modern quality management.

    Scandinavian journal of clinical and laboratory investigation·2000
    Same author

    Points of care in using statistics in method comparison studies.

    Clinical chemistry·1998
    Same author

    Comparison of NCEP performance specifications for triglycerides, HDL-, and LDL-cholesterol with operating specifications based on NCEP clinical and analytical goals.

    Clinical chemistry·1997
    Same author

    Quality control for qualitative assays: quantitative QC procedure designed to assure analytical quality required for an ELISA of hepatitis B surface antigen.

    Clinical chemistry·1997
    Same journal

    Indirect methods for the verification of reference intervals in laboratory medicine.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Sustainability and waste reduction in clinical laboratories.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Aptamer-based biosensing strategies for influenza virus detection: a systematic and critical review of electrochemical and optical platforms.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Advancing patient safety through laboratory quality indicators in clinical pathology.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Blood biomarkers for the diagnosis of chorioamnionitis following preterm premature rupture of membranes: a systematic review and meta-analysis of studies since 2020.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Single cell mechanodeformation signatures as early biomarkers for hematological malignancies.

    Critical reviews in clinical laboratory sciences·2026
    See all related articles

    This review explains how to achieve precision and accuracy in clinical analyses by identifying and eliminating analytical errors. It details method evaluation experiments for assessing analytical performance and ensuring reliable results.

    Area of Science:

    • Clinical Chemistry
    • Analytical Science
    • Laboratory Medicine

    Background:

    • Routine clinical analyses demand high precision and accuracy.
    • Identifying and eliminating sources of analytical error is crucial for reliable patient results.
    • Understanding fundamental concepts of measurement, error, and statistical control is essential.

    Purpose of the Study:

    • To review the fundamental concepts of precision and accuracy in analytical chemistry.
    • To describe method evaluation experiments for assessing the performance of analytical methods.
    • To provide a framework for ensuring the reliability of clinical analyses.

    Main Methods:

    • Discussion of core concepts: measurement process, analytical method, statistical control, precision, accuracy, error types, traceability.

    Related Experiment Videos

  • Description of method evaluation experiments: familiarization, range/linearity testing, precision assessment (replication), accuracy assessment (recovery, interference, method comparison).
  • Emphasis on developing evaluation protocols based on analytical characteristics and statistical analysis of comparison data.

    • Main Results:

    • Established a clear understanding of precision and accuracy, and their associated error types.
    • Outlined a systematic approach to method evaluation experiments.
    • Provided a basis for evaluating and selecting analytical methods based on performance characteristics.

    Conclusions:

    • Rigorous evaluation of analytical methods is essential for achieving precision and accuracy in clinical analyses.
    • A comprehensive understanding of concepts and systematic experimental approaches ensures reliable diagnostic information.
    • This review provides a foundation for improving the quality and dependability of laboratory testing.