Related Experiment Videos
[Vaginal fungi in toxemia of pregnancy (author's transl)]
Abstract:
In order to prevent the transfer of the fungi in maternal vagina into a neonate through transvaginal delivery, we examined the presence of vaginal fungi in the patients with toxemia of pregnancy occurring chiefly from the later stages of pregnancy and made an analysis from the quantitative aspect of fungi (number of colonies produced on Mizuno-Takada medium). The results obtained are as follows: 1) The detection rate of vaginal fungi was evidently so high as 37.1% in toxemia group compared with 27.6% in non-toxemia group (p less than 0.01). And the detection rate of vaginal Candida albicans (hereinafter: C. albicans) also proved to be higher tendency in toxemia group. 2) When the toxemia patients were divided into mild cases and severe ones for comparison, the detection rate of vaginal fungi and that of vaginal C. albicans were both higher in the severe case group. Particularly in the group which had the symptoms of toxemia at the examination time of vaginal fungi there was seen the higher rate. 3) From the quantitative aspect of vaginal fungi it is evident that there were more cases with over 51 colonies in the group showing the symptoms of toxemia at the time of fungi examination than in the group showing no such symptoms at the examination and the group of non-toxemia (p less than 0.01).
Insights
Pregnant individuals with toxemia show higher rates of vaginal fungi, including Candida albicans. Severe toxemia cases exhibit increased fungal detection, suggesting a link between toxemia and vaginal fungal presence during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Medical Mycology
- Maternal-Fetal Medicine
Background:
- Vaginal fungal infections can pose risks during childbirth.
- Toxemia of pregnancy, a serious condition, may influence the vaginal microbiome.
Purpose of the Study:
- To investigate the prevalence and quantity of vaginal fungi in pregnant patients with toxemia.
- To assess the potential association between toxemia of pregnancy and vaginal fungal colonization.
Main Methods:
- Vaginal fungal presence was examined in pregnant patients.
- Fungal detection rates and colony counts (using Mizuno-Takada medium) were analyzed.
- Patients were categorized into toxemia and non-toxemia groups, and toxemia severity was considered.
Main Results:
- Vaginal fungi were detected in 37.1% of toxemia patients versus 27.6% in non-toxemia controls (p<0.01).
- Candida albicans detection was also higher in the toxemia group.
- Severe toxemia cases and those with active symptoms showed significantly higher fungal detection rates and colony counts.
Conclusions:
- Toxemia of pregnancy is associated with a higher prevalence and quantity of vaginal fungi.
- Increased vaginal fungal load in toxemia patients may warrant further investigation for neonatal transmission risks.