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Related Experiment Videos

Shigella and shigellaemia

P De Mol, D Brasseur, E Schatteman

    Scandinavian Journal of Infectious Diseases
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    This study highlights two pediatric cases of Shigella flexneri 2a bacteremia. The findings demonstrate the diverse clinical presentations of shigellosis, from mild gastroenteritis to severe sepsis with extra-intestinal complications.

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    Area of Science:

    • Pediatric Infectious Diseases
    • Microbiology
    • Clinical Medicine

    Background:

    • Shigellosis is a significant cause of diarrheal disease globally.
    • Shigella flexneri 2a is a common serotype responsible for shigellosis.
    • Bacteremia is a severe complication of shigellosis, particularly in children.

    Observation:

    • Two pediatric cases of bacteremia caused by Shigella flexneri 2a were documented.
    • Clinical presentations varied significantly between the two cases.
    • One case presented with symptoms consistent with benign gastroenteritis.

    Findings:

    • The cases illustrate the broad spectrum of clinical manifestations associated with Shigella flexneri 2a infections.
    • Severe extra-intestinal manifestations were observed in conjunction with sepsis.

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  • Bacteremia indicates a systemic spread of the infection.

    • Implications:

    • Early recognition of diverse clinical signs is crucial for timely diagnosis and management of shigellosis.
    • Understanding the range of presentations can improve clinical suspicion for severe cases.
    • This underscores the importance of considering Shigella in the differential diagnosis of pediatric sepsis, even with seemingly mild initial symptoms.