In vitro tests for platelet compatibility

Four methods were investigated to determine their suitability as platelet compatibility procedures: leukoagglutination, lymphocytotoxicity, platelet suspension immunofluorescence and platelet enzyme-linked immunosorbant assay. None of the tests were found to reliably predict the 24-hour-posttransfusion platelet increment in 8 refractory thrombocytopenic patients judged refractory to random donor platelet therapy.